Ischemic heart disease is a common consequence of coronary artery disease (CAD), which is primarily driven by atherosclerosis, a chronic inflammatory ...

Using its proprietary T-cell Activation Platform (TCAP), the company ... Immune Pan-antigen Cytotoxic Therapy ( ImPACT) and Combination Pan-antigen Cytotoxic Therapy ( ComPACT).

Cytotoxic T cells ... that the cellular architecture of T cells influences which of these two functions the cells adopt when they undergo pathogen-induced activation. As well as improving our ...

In March 2025, Juventas Cell Therapy Ltd. conducted a phase Ib/II trial to evaluate the safety and efficacy of CNCT19 ...

The scRNA-seq results revealed that dietary antigens influence the activation of T- and dendritic ... PPs in response to food antigens. Cytotoxic T-cell activity is a crucial aspect of antitumor ...

Others attract more T cells or cell-eating phagocytes. Killer T cells (cytotoxic T lymphocytes) attack other cells. They are particularly useful for fighting viruses. They work by recognizing ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...