The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All cytoskeletons consist of three major ...

Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells with mechanical resilience, as well as assisting with cell division.

Caltech researchers demonstrated a new method to use light to control active matter—a kind of material made up of individual ...

The research focuses on cells’ “feet,” which are small bundles of molecules that help cells move. Scientists are exploring ...

For example, humans alone have over 20 different kinds of integrins. Integrins link the actin cytoskeleton of a cell to various external structures. The cytoplasmic portion of each integrin ...

In our lab, we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton and cellular adhesions ... approach combining state-of-the-art techniques in cell biology, biochemistry ...

Cleaving hundreds of different kinds of proteins within a cell, these enzymes wreak havoc on the genome, attack structural proteins composing the cell’s organelles, and dismantle the cytoskeleton, ...

Mark Groudine Chair for Outstanding Achievements in Science and Service, Fred Hutch Mark Groudine Chair for Outstanding Achievements in Science and Service Fred Hutch Dr. Susan Parkhurst studies the ...

We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...

Our ultimate goal is to define if manipulating the cytoskeleton of cancer cells will lead to improved efficacy of therapeutic approaches in patients with metastatic disease, with a special focus on ...