Figure 1: Stepwise evolution of DNA on the basis of what is inferred from modern biochemical pathways. Figure 4: 'Leaky' mismatch-specific uracil-DNA glycosylase as a driving force for evolution of ...
NASA scientists studying the origin of life have reproduced uracil, cytosine, and thymine, three key components of our hereditary material, in the laboratory. They discovered that an ice sample ...
With dienes as specific triplet quenchers, it has been shown that the photodimerization of thymine in acetonitrile proceeds entirely through the triplet state and the photodimerization of uracil in ...
A schematic showing the cytosine base editing intermediate and the various outcomes that can occur when the UNG protein is active. You may have seen it in the news recently: a baby in Pennsylvania ...
Three of the five nucleobases --- molecular subcomponents of information-bearing nucleotides which make up our genetic code --- likely came from space. But the origins of two key components of RNA and ...
The DNA of all organisms consists of the four bases adenine, cytosine, thymine and guanine, which are abbreviated using the letters A, C, T and G. In RNA, thymine is replaced by uracil (U). The bases ...
Methylating agents are widespread environmental carcinogens that generate a broad spectrum of DNA damage. Methylation at the guanine 0⁶ position confers the greatest mutagenic and carcinogenic ...
How did life come about? The answer to this question goes to the very heart of our existence on planet Earth. Did life simply arise from chemical reactions among organic compounds in a primordial soup ...
Left to right: Ames scientists Michel Nuevo, Christopher Materese and Scott Sandford reproduce uracil, cytosine, and thymine, three key components of our hereditary material, in the laboratory.
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