Isothermal titration calorimetry (ITC ... In a displacement titration, the association constant of a high-affinity ligand that cannot be measured directly is artificially lowered to a measurable ...

This tutorial describes the use of Isothermal Titration Calorimetry (ITC ... [see equation 1 on left]where k1 is the rate constant for formation of ES and k-1 is the rate constant for dissociation ...

Isothermal titration calorimetry (ITC) is an analytical technique ... The titration is performed at constant pressure and temperature, meaning that a single ITC experiment offers data on the binding ...

While pressure and volume are readily measurable ... enthalpy changes occur at constant pressure, linking these changes to the heat absorbed or produced by the reaction. This type of calorimetry is ...