But the complement system is an oft-overlooked part of the immune system that could be exploited to create new therapies. It’s more than a decade since the first checkpoint inhibitor hit the ...

In the EU, GOHIBIC (vilobelimab) has been granted marketing authorization under exceptional circumstances for the treatment ...

A complement blood test checks for autoimmune diseases or other issues with your immune system. Your doctor might test you if you have a family history of certain conditions, such as rheumatoid ...

Now, over 100 years after the complement system was first described, researchers at Mass General Brigham have discovered that a protein known as granzyme K (GZMK) drives tissue damage and ...

A study by researchers from The University of Manchester and Cambridge into attitudes to the use of AI in general practice ...

Cleveland Clinic: “Glomerular Diseases,” “Complement System.” NORD: “NIH GARD Information: Dense deposit disease,” “C3 Glomerulopathy: Dense Deposit Disease and C3 Glomerulonephritis.” ...

Brenner: Complement is an ancient system driving inflammation and host defense in humans. Importantly, there are three different ways complement can get activated.

“When it binds those, it actually by itself starts cleaving the components, cutting those proteins that are involved in the complement system, and generating the same mediators that will usually ...