But the complement system is an oft-overlooked part of the immune system that could be exploited to create new therapies. It’s more than a decade since the first checkpoint inhibitor hit the ...

A complement blood test checks for autoimmune diseases or other issues with your immune system. Your doctor might test you if you have a family history of certain conditions, such as rheumatoid ...

A study by researchers from The University of Manchester and Cambridge into attitudes to the use of AI in general practice ...

Now, over 100 years after the complement system was first described, researchers at Mass General Brigham have discovered that a protein known as granzyme K (GZMK) drives tissue damage and ...

Brenner: Complement is an ancient system driving inflammation and host defense in humans. Importantly, there are three different ways complement can get activated.

When the macular area is involved, it develops into DME 2. Additionally, complement system activation contributes to disease progression by damaging the neurovascular units through cytolysis, ...

“You could see little parts of the human cell being broken off,” Ralston said of her very first encounter with the parasite.

“When it binds those, it actually by itself starts cleaving the components, cutting those proteins that are involved in the complement system, and generating the same mediators that will usually ...