Efficacy and safety of durvalumab plus tremelimumab versus standard chemotherapy for non-small cell lung cancer: A systematic review and meta-analysis of phase III randomized controlled trials. This ...

Integrated Epigenetic and Transcriptomic Analysis Identifies Interleukin 17 DNA Methylation Signature of Malignant Peripheral Nerve Sheath Tumor Progression and Metastasis Presented in part at ESMO ...

Tumor-infiltrating clonal hematopoiesis (TI-CH ... as a potential target for interventions that regulate tumor progression and metastasis in solid cancers." However, "many questions remain ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele ...

Characterizing clonal evolution in blood cancers like acute myeloid leukemia (AML) is critical for understanding their mutational histories and how cell populations change during disease development.

Get Instant Summarized Text (Gist) A genetic signature of 177 genes has been identified as a common driver of metastasis across various cancer types. Key genes include SP1, which accelerates ...

Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene. Metastasis is ...