TI-CH remodeled the tumor immune microenvironment and accelerated tumor organoid growth, findings that support a role for an aging-related hematologic clonal proliferation in cancer evolution.

These alterations are reflective of underlying tumor cell clonal evolution with selection for clones harboring resistance mechanisms in the presence of initially effective treatment. The responses to ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...