So when Christina Applegate received her own "devastating" diagnosis and reached out to her for help, The Sopranos alum was open to offering advice. "I wanted to give her tools and things that I ...

During Tuesday's episode of her MeSsy podcast with Jamie-Lynn Sigler, Applegate referenced her own health battle as she gave a listener—who was struggling with diarrhea and vomiting—some advice.

Christina Applegate's podcast with Jamie-Lynn Sigler delves into their battles with anorexia and MS. Applegate's Married with ...

Sagal also noted that she worried about how growing up on the set of a sitcom might affect Applegate. “I always felt very much like Christina grew up very quickly and had a sense of maturity ...