NIH’s SMaHT Network will chart trillions of somatic mutations to reveal how our DNA changes over a lifetime. In a nutshell ...

To address this gap, the study leveraged 64,000 fully synthetic DNA sequences to dissect the design principles of cell-state specific enhancers during differentiation of blood stem cells to seven ...

With Cell Painting screening we can now rapidly probe libraries of these compounds using SPACe to study them and uncover their potential therapeutic value.” Future studies will evaluate the safety and ...

AI-designed DNA controls genes in healthy mammalian cells for first time ... Design principles of cell-state-specific enhancers in hematopoiesis. Cell, 2025 DOI: 10.1016/j.cell.2025.04.017; ...

Human and chimpanzee neural progenitor cells and cortical organoids were analyzed to assess enhancer activity and cell proliferation.. Genome editing was employed to generate mouse models ...

Cell & Microbiology; May 22, 2025 The GIST. Ancient DNA used to ... Ancient DNA analysis of Borrelia recurrentis reveals it diverged from its tick-borne ancestor B. duttonii 6,000–4,000 years ...

Residual HEK293 DNA in biotherapeutic candidates can harbor tumorigenic or retroviral sequences that run the risk of transmission to human recipients, making accurate HEK293 DNA quantification ...