Z-VAD-fmk blocks hippocampal neuronal loss. The peptide z-VAD-fmk is a broad-spectrum caspase inhibitor that effectively delays apoptosis in many cell types 14,15,16.To assess its potential ...

TREAT-ME 1: Treatment of advanced gastrointestinal cancer in a clinical phase I/II trial with genetically modified mesenchymal stem cells: Clinical results of a phase I study. An open-label, ...

SAN DIEGO, April 09, 2018 (GLOBE NEWSWIRE) -- Conatus Pharmaceuticals Inc. (NASDAQ:CNAT), a biotechnology company focused on the development of ...

Amerimmune LLC Maintains Intellectual Property on the COVID-19 Related Use of Caspase Inhibitors as a Result of Histogen Inc. Led Arbitration January 18, 2023 02:02 PM Eastern Standard Time ...

“This is the second allosteric TYK2 inhibitor we have advanced into the clinic this year, after SUDO-286 which is progressing in two Phase 1 trials as a topical treatment for psoriasis.” ...

C1 inhibitor protein is predominantly expressed in the liver, which has led to the suggestion that hereditary angioedema can be viewed as a metabolic liver disorder. 6 One group reported a case of ...

ROCKVILLE, Md. and SUZHOU, China, June 02, 2025 (GLOBE NEWSWIRE) -- Ascentage Pharma (NASDAQ: AAPG; HKEX: 6855), a global biopharmaceutical company dedicated to addressing unmet medical needs in ...

Bayer’s Vividion Therapeutics has secured the global rights from its partner Roche to the only covalent Werner helicase (WRN) inhibitor to have made it into the clinic.. Vividion and Roche have ...

Topical BRAF inhibitor LUT014 gel significantly reduces acneiform rash from anti-EGFR therapies in patients with colorectal cancer. News & Perspective Tools & Reference CME/CE. More .

NS-229 is an investigational selective Janus kinase 1 inhibitor designed to prevent tissue damage caused by EGPA by suppressing immune cell activation.

Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark of apoptosis initiation—with fluorescent dyes. Researchers often perform multiplex caspase assays ...