Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

New research shows that cancer cells don’t just grow; they adapt when stressed. When squeezed inside tissues, they transform ...

Every time a eukaryotic cell divides, it faces a monumental challenge: It must carefully duplicate and divide its genetic ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

Pressure from surrounding tissues activates invasive programs in cancer cells. This mechanical stress rewires epigenetic regulation. Cancer cells are notoriously adaptable, capable of shifting their ...

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on ...

Plasticity in cancer cells describes their inherent ability to undergo alterations and turn certain features on and off at different times.  This flex | Cancer ...

New research published in Immunity by researchers at the University of Pittsburgh found that, in mice, the toxic tumor environment causes mitochondria to generate reactive oxygen species (ROS) that ...

A mixture of DNA and proteins—known as "chromatin"—sits inside every cell nucleus as a jumbled puddle of genetic information. As cells prepare to divide during mitosis, the chromatin is condensed into ...

Telomere damage drives T cell exhaustion. Antioxidants restored their cancer-fighting strength in mice. Tumor environments place heavy stress on immune cells that fight cancer. Limited oxygen, ...

To make the behavior of DNA understandable and predictable, the researchers combine lab experiments with computer simulations ...