To completely understand the interaction of CYP2D6 and tamoxifen effectiveness, future research should be directed at some critically important, but, understudied areas. First, a comprehensive ...
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Study Renews Warning on Antidepressant, Painkiller Combo
Used for decades, tramadol is a commonly prescribed opioid agonist. Its label warns that seizures can occur within the recommended dose range and that concomitant use with certain other drug can raise ...
Functional Activity of the OCT-1 Protein Is Predictive of Long-Term Outcome in Patients With Chronic-Phase Chronic Myeloid Leukemia Treated With Imatinib Evidence has emerged that the clinical benefit ...
Aim We sought to discover endogenous urinary biomarkers of human CYP2D6 activity. Patients & Methods Healthy pediatric subjects (n = 189) were phenotyped using dextromethorphan and randomized for ...
Clinical recommendations discouraging the use of CYP2D6 gene testing to guide tamoxifen therapy in breast cancer patients are based on studies with flawed methodology and should be reconsidered, ...
SAN DIEGO, March 16, 2017 /PRNewswire/ -- CogenDx, which offers genetic testing to identify how a patient's genetic profile may impact his or her response to certain medications, unveils one of the ...
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