The structure of complement protein C3 reveals a large, modular protein consisting of 13 domains with a buried thioester moiety. Proteolytic activation of C3 into C3b induces conformational ...

For all complement-activating antibodies, C3b deposition on the surface of K. pneumoniae caused activation of complement-mediated phagocytosis and elimination by human neutrophils. Antibody ...

A section through the retinal pigment epithelium layer from an infected ACE2-expressing mouse: upper image, bright-field plus SARSCoV-2 N-protein (green) and complement component C3b ...

A) Complement is activated trough three pathways leading to C3b opsonization, release of anaphylatoxins (C5a) and formation of membrane attack complexes (MAC). Factor H (FH) regulates complement at ...