Researchers have identified two distinct mechanisms of drug resistance in C. difficile, but its ability to withstand antibiotics comes with downsides for the bacteria.

C. diff, which is short for Clostridioides difficile, is a type of bacteria that may cause serious problems in the digestive ...

Vancomycin has long been the go-to antibiotic of choice against C. difficile, with its use jumping 54% in the past six years, according to Garey and colleagues.

Recurrent C. difficile incidence during treatment and the 8-week follow-up period served as the primary outcome. Evidence of vancomycin-resistant Enterococcus in stool was the secondary outcome.

The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research.

Clostridium difficile-associated disease has been treated with metronidazole and/or vancomycin for the past 25 years. Each drug offers its own treatment benefits, but are they as effective nowadays?

Researchers said the link between vancomycin and C. Difficile recurrence may have something to do with the severity of inflammatory bowel disease, and after treatment there may also be increased rates ...

1. There were no cases of C. diff infection in patients that received oral vancomycin. 2. However, 11 of the 55 patients who did not receive vancomycin developed C. diff during the transplantation. 3.

Vacnomycin has been the gold-standard antibiotic for treating C. diff and many other life-threatening infections since its introduction in 1965. “It’s a great drug.