C. diff infects around 500,000 patients every year in the US, triggering symptoms including diarrhea, abdominal pain and fever. Of these, about 30,000 die from the infection.

While many people have C. diff bacteria, there’s no need for treatment if a person has no symptoms. Treatment is typically recommended if you have symptoms and test positive for C. diff.

Importantly, not all C. diff bacteria cause disease, and most of the C. diff spread the researchers observed involved harmless bacterial varieties.

Importantly, not all C. diff bacteria cause disease, and most of the C. diff spread the researchers observed involved harmless bacterial varieties.

In the United States, an estimated 15,000 to 30,000 deaths per year are linked to C. diff. Risk factors for recurrent infection include being 65 or older, hospitalization, being in a nursing home ...

Clostridioides difficile (C. diff), a type of bacteria which often affects people who have taken antibiotics, is responsible for approximately 2,000 deaths annually in the UK.

But C. diff is a particularly hard kind of bacteria to kill. It has become resistant to some antibiotics — and it has the capacity to hide from them, lay low, and then cause a relapse.

SAB has advanced its preclinical program, SAB-195, a polyclonal antibody treatment for C. diff., one of the most prevalent healthcare-associated bacterial infections in the US and the developed world.

Normally, the harmful C. diff bacteria are far outnumbered by other bacteria in our intestines. These other bacteria keep C. diff under control. For this reason, we’ll call them “good” bacteria.

An mRNA vaccine designed to target C. difficile and the toxins it produces protected mice from severe disease and death after exposure to lethal levels of the bacterial pathogen, researchers ...