View Full Profile. Learn about our Editorial Policies. When I expressed the different protein constructs in neuron cells in culture, I demonstrated that these C-terminal tails determined the ...

These proteins are also referred to as C-terminal amide-bearing proteins (CTAPs). CTAPs emerge from cleavage of the protein ‘backbone’ during oxidative stress (Fig. 1). This cleavage involves ...

C-terminal amidation is a PTM that involves the addition of an amid group to the C-terminus of a peptide or protein. Currently there is no direct evidence to suggest that C-terminal amidation of ...

at the protein's end or C-terminus, which was key to this process. "Unlike typical peroxisomal targeting signals, the PTS of HSR201 is unique and does not fit the usual consensus sequence.

Researchers at UT Southwestern identified how SNX17 and Retriever interact to regulate endosomal recycling, a crucial process ...

In many instances, the Ub/Ubl-modified protein is specifically recognized by downstream ... the anti-recombinogenic helicase Srs2 and we were able to determine that its C-terminal domain harbored ...