Lipid nanoparticle platform delivers mRNA to the brain
Designing BBB organoids posed a technical challenge: growing the two components—the brain ... blood vessels in the BBB. In contrast, blood vessel organoids did not express these molecules before ...
The delivery challenge is posed by the blood–brain barrier (BBB), which prevents around ... Published in vitro and in vivo studies by NEUWAY have validated the transport of EnPCs across the ...
7don MSN
For decades, scientists across the globe have investigated methods to accurately measure drug permeability across the blood-brain barrier, a compact layer of cells that protect the brain from ...
Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...
The findings revealed a novel mechanism through which microplastics indirectly disrupt vascular and neurological functions without crossing the blood-brain barrier ... in vivo, are poorly ...
They were watching brain scans of a woman named Bonny Hall, who lay inside an MRI machine just a few feet away. Earlier that day, Hall, who had been battling a brain tumor for eight years, had ...
glial cells and the blood-brain barrier following ischemic insult. We also describe the evidence of TRPM2 involvement in these processes, as shown from numerous in vitro and in vivo studies that ...
The Blood-Brain Barrier Summit will take place online from June 28-30, 2021. This Hanson Wade event is aimed at experts looking to deliver CNS drug candidates safely and successfully across the ...
Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback