B cell development in swine presents a unique model within mammalian immunology. In contrast to traditional murine and human systems, swine exhibit notable differences in the temporal order of heavy ...
Project Title: Assessing the Role of SHP2 on B Cell Proliferation in a Lupus Mouse Model Project Summary: Lupus is a disease affecting 1.5 million Americans. While the exact causes of lupus are ...
When the genetically altered mice were just 18-20 months old, the lack of ELOVL2 enzymatic activity decreased the expression of several genes related to B cell development in their bone marrow. In ...
Aera Therapeutics Presents Preclinical Data and Announces Nomination of First Development Candidate, AERA-109, a Targeted In Vivo CAR-T Therapy for B Cell-mediated Autoimmune Diseases Preclinical data ...
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