scientists could only study autophagy by examining cells with electron microscopes. Using this tool, they established that after autophagosomes form, they fuse to the lysosomal membrane to form a ...

Prior to this, autophagosomes could only be captured with an electron microscope due to its small size. It had become possible to observe when, where and how autophagy is occurring in real-time. In ...

Understanding the physiological regulation and significance of selective autophagy may lead to a variety of new ... the state-of-the-art in vivo imaging and electron microscopy. Embedded within one of ...