Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 52 (December 26, 2019), pp. 26941-26950 (10 pages) Autophagy is a powerful host defense that restricts ...

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell ...

Autophagy contributes to the homeostasis of a cell and recently another function of autophagy has been reported. A KAIST research team found that the autophagy of dendritic cells supports T-cell ...

Proteins classically associated with autophagy regulate the speed of intracellular transport. Scientists from the laboratory of Dr. Natalia Kononenko at the CECAD Center of Excellence in Aging ...

There are three main types of autophagy in mammalian cells: macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). Each of these pathways converges in lysosomes to ensure ...

Autophagy is a vital process in which the body’s cells “clean out” any unnecessary or damaged components. It may be possible to induce autophagy, but there may be associated risks. Researchers have ...

Unfolded protein response (UPR) is comprised of complex and conserved stress pathways that function as a short-term adaptive mechanism to reduce levels of unfolded or misfolded proteins and maintain ...

Autophagy is a critical cellular process that removes damaged organelles and recycles nutrients to maintain homeostasis. In cancer, autophagy plays a complex role, supporting tumor suppression and ...