Nature19d
Apoptosis in animal models of virus-induced disease
106). Effector caspases (such as caspase 3) function primarily to cause the morphological features of apoptosis. Specifically, activation of caspase 3 leads to the breakdown of several ...
Armed robbery in Revesby3d
Bacterial Effector Alters Host Cell Death to Aid Infection
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis ...
How M. tuberculosis alters host cell death mechanisms to facilitate infection
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
Nature15d
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Cell death is achieved by two fundamentally different mechanisms: apoptosis and necrosis. Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway ...