6 13 Genetic deficiency in apoE and also the presence of apoɛ2 and apoɛ4 genes in the population are associated with predisposition to atherosclerosis and Alzheimer's disease, respectively.

The APOE gene encodes apolipoprotein E ... People who inherit APOE4 have an elevated risk of atherosclerosis due to high levels of circulating cholesterol. In contrast, those who inherit APOE2 ...

This condition, also known as familial dysbetalipoproteinemia, is characterized by elevated cholesterol and triglyceride levels in blood, and early onset atherosclerosis and heart disease. The proband ...

ApoE-knockout mice-which develop spontaneous hypercholesterolemia and atherosclerosis after about four months and neurodegeneration after eight months-crossed with aP2-knockout mice had up to 87 ...

Atherosclerosis is the buildup of fats ... The apolipoprotein E-null (ApoE −/−) mice model is an extremely popular murine representative of human lesions. Studies using this in vivo system ...

The most widely used model of atherosclerosis is a mouse lacking the protein “apolipoprotein E”, or ApoE. Using mice without ApoE that they engineered to also lack Favine, the team observed ...

In previous work, Tavazoie's lab studied a gene called APOE that plays a role in cancer ... are at greater risk of developing Alzheimer's and atherosclerosis, and Tavazoie and Benjamin Ostendorf ...

Atherosclerosis is the major contributor to ... ADF intervention might contribute to the worsened atherosclerosis in Apoe-/- mice fed with WD. Meanwhile, the study indicated that ADF inhibited ...

Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events. A key process in atherosclerosis is ...