The microbial ecosystems in our mouths may impact cognitive function as we age, with pathogenic bacteria linked to cognitive ...

The study found increased permeability in the blood-brain barrier of APOE4 carriers, including those without cognitive symptoms or amyloid beta buildup. The blood-brain barrier is a critical ...

Projected rates were highest in Black adults, women, and APOE4 carriers. Dementia cases in the U.S. are expected to double in the next four decades, a new analysis suggested. In a racially and ...

Oral bacteria may impact brain health, and diet could help preserve cognitive function. The bacteria in your mouth may play a ...

Apolipoprotein E epsilon 4 (APOE4) is the primary genetic risk factor for late-onset Alzheimer's disease (AD). APOE4 carriers, especially females, tend to develop gut dysbiosis earlier than ...

However, in people with mild cognitive impairment, the presence of depressive symptoms was tied to a lower likelihood of amyloid pathology (OR 0.73, 95% CI 0.61-0.89, P =0.001), Oomens and colleagues ...

The microbial ecosystems within our mouths may affect our cognitive function as we age, according to a study. Interventions ...

The equivalent figure for women is 25–35 ml/kg/min. Among the 640 participants who were genotyped, 174 (27%) were APOE4 carriers. As expected, older age was associated with poorer performance across ...

Data show the lifetime risk for developing dementia after age 55 years is 42% in the U.S. The lifetime risk was higher — between 45% and 60% — among women, Black adults and APOE4 carriers.

FDG-PET is able to evaluate treatment efficacy in late to middle-age APOE4 carriers. Genetic effects, interventions or treatment efficacy (e.g., diet, exercise and pharmaceutical approach ...