This region is called the ''Fc (Fragment, crystallizable) region''. In this area are two heavy chains that contribute two or three constant domains depending on the class of the antibody.

The most commonly used antibody fragment format is the Fab format, but it is difficult to produce in bacterial expression systems because of its large and complex structure.

Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability. Structure, 2017; DOI: 10.1016/j.str.2017.08.011 ...

Understanding these glycosylation patterns is just as important as analyzing other tools like labeled peptides, which are ...

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal ...

Wiesner first developed them more than 15 years ago and, in collaboration with Bradbury, published a 2018 study that found an antibody fragment-nanoparticle hybrid to be especially effective in ...

Discovery of antibody structure could lead to treatment for Crimean Congo Hemorrhagic Fever virus Study provides insights into fighting broad range of pathogen's viral strains Date: November 29 ...

A study suggests that a nanobody that alpacas produce naturally may help prevent infection with SARS-CoV-2, which is the coronavirus that causes COVID-19.