The schematic structures resulting from 3D domain swapping of the variable region #4V L (yellow) in the light chain #4C214A (yellow and light gray) of an antibody.

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains ...

David M. Kranz, Edward W. Voss, Restricted Reassociation of Heavy and Light Chains from Hapten-Specific Monoclonal Antibodies, Proceedings of the National Academy of Sciences of the United States of ...

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains.

The second light chain antibody fragment, hk14, demonstrated carboxypeptidase-like activity, cleaving sequentially from the carboxyl terminal of beta amyloid. In a more recent study by the same group, ...

Susumu Tonegawa, Reiteration Frequency of Immunoglobulin Light Chain Genes: Further Evidence for Somatic Generation of Antibody Diversity, Proceedings of the National Academy of Sciences of the United ...

TORONTO, ON/ ACCESSWIRE/ April 20, 2020/ Edesa Biotech, Inc., a clinical-stage biopharmaceutical company, today announced a strategic agreement with Light Chain Bioscience, a leading Swiss ...

The monoclonal antibodies licensed from Light Chain Bioscience block certain signaling proteins, known as TLR4 and CXCL10. These molecules are associated with a broad range of diseases, including ...