Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43443-4 ...

The schematic structures resulting from 3D domain swapping of the variable region #4V L (yellow) in the light chain #4C214A (yellow and light gray) of an antibody.

Maerivoet, A., et al. (2024) Enhanced stabilisation and reduced fibril forming potential of an amyloidogenic light chain using a variable heavy domain to mimic the homodimer complex. The FEBS ...

On June 12th, 2023 local time, Sanyou Biopharmaceuticals Co., Ltd. officially announced the launch of "Sanyou Super Trillion Common Light Chain Antibody Discovery Platform" (the "platform").

Susumu Tonegawa, Reiteration Frequency of Immunoglobulin Light Chain Genes: Further Evidence for Somatic Generation of Antibody Diversity, Proceedings of the National Academy of Sciences of the United ...

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Background: Talaporfin sodium (TS) is a light-activated, locally cytoreductive drug in phase III clinical trials for several different cancers. It is activated intratumorally with a thin, flexible LED ...