Our study shows how a small antibody fragment can block fertilization by targeting ZP2, a key protein in the outer layer of the egg that is involved in both sperm binding and blocking polyspermy." ...

Mar 16, 2023: Antibody fragment-nanoparticle therapeutic eradicates cancer (Nanowerk News) A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, ...

Antibody fragment-nanoparticle therapeutic eradicates cancer. Cornell University. Journal Advanced Therapeutics DOI 10.1002/adtp.202200209 ...

An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. ACS Chemical Neuroscience, 2023; DOI: 10.1021/acschemneuro.3c00455; ...

Immunosensors are widely used in immunoassays to detect antigens. One such immunosensor is a quenchbody (Q-body), which contains a modified antibody fragment with a quenched fluorescent dye. When ...

KaloBios Pharmaceuticals is to receive $35 million up front from Sanofi Pasteur as part of the companies’ collaboration to develop KaloBios’ Phase II-stage antibody fragment KB001 for treating ...

In this phase 1, double-blind trial, we randomly assigned (in a 2:1 ratio) 40 patients with wild-type or variant ATTR cardiomyopathy and chronic heart failure to receive intravenous infusions of ...

An antibody that binds to fentanyl, reported recently in ACS Chem. Neurosci. (2023, DOI: 10.1021/acschemneuro.3c00455), is also scheduled to start clinical trials later this month.

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal ...