Tumor necrosis factor-related apoptosis ... TRAIL-sensitive tumor cells in vitro along with perforin and Fas ligand (FasL). Administration of neutralizing monoclonal antibody against TRAIL ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Bispecific antibodies, which bind simultaneously ... target combination are very effective at inducing apoptosis of tumor stem cells,” said Logtenberg. Preclinical studies show that MCLA-158 ...

An investigational therapy significantly shrank lung cancer tumors that are notoriously resistant to treatment by encouraging ...

They observed that these cells were unable to proliferate and became stuck in the DNA replication phase. These cancer cells also expressed high levels of proteins that cause DNA breaks ... growth and ...