This commentary highlights the potential of an alternate regressive method for biochemical pathway design and generation ... illustrated with the biosynthesis of pHPG (4), a component of ...

In this work, they focused on peptide condensation of two key modules involved in producing tyrocidine B, a natural antibiotic ... which helps ensure the pathway runs smoothly.

The biochemistry that the researchers learn from this study will enhance the understanding of a group of enzymes involved in the biosynthesis of natural products with antibiotic and anticancer ...