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Bacterial proteins are synthesized with an N-formylated amino-terminal methionine ... proteins are co-translationally deformylated by peptide deformylase. Here we develop a deformylation assay ...
N-terminal sequencing targets the amino-terminal (N-terminal) end of a protein or peptide, which corresponds to the first ... results—such as when peptides lack fragmentation or exhibit signal ...
Despite an alarming increase in morbidity and mortality caused by multidrug-resistant bacteria, the number of antibiotics available to efficiently combat them is dwindling. Consequently, there is ...
This segment turned out to be an 18-amino-acid sequence, which the team termed Exosome Binding Peptide (EBP). The team found that “addition of EBP to an unrelated protein directed secretion on ...