In contrast to relapsing‐remitting patterns, persistently active disease (PAD) is a disease activity pattern in patients with systemic lupus erythematosus (SLE) that is inadequately studied.

A large prospective multinational cohort study, published in ACR Open Rheumatology, found that nearly 10% of patients with SLE experienced PAD but not flare, indicating flare-related interventions ...

The American College of Rheumatology (ACR ... of CLE patients who experienced systemic reactions after sun exposure despite not meeting criteria for SLE. A small study of a subset of the ...