People who carry two APOE4 copies, known as APOE4 homozygotes, have an estimated 60% chance of developing AD dementia by the age of 85.

Seven years of investigation by scientists at Harvard Medical School has revealed that the loss of the metal lithium plays a ...

People who carry two copies of the gene mutation most strongly implicated in Alzheimer's disease are almost certain to develop brain changes related to the degenerative disorder, a new study says.

People who carry two copies of the APOE4 gene are virtually guaranteed to develop Alzheimer's and face symptoms at an earlier age, researchers reported on Monday in a study that could redefine ...

An estimated 15% of Alzheimer’s patients carry two copies of APOE4, meaning those cases “can be tracked back to a cause and the cause is in the genes,” Fortea said.

An estimated 15% of Alzheimer’s patients carry two copies of APOE4, meaning those cases “can be tracked back to a cause and the cause is in the genes,” Fortea said.

Familial forms, caused by mutations in any of three genes, tend to strike earlier and are known to be rare, accounting for about 2% of all Alzheimer’s diagnoses, or about 1 in 50 cases.

Saiyaara shows early-onset Alzheimer’s in a 22-year-old girl. Experts explain this rare but serious brain disorder that can affect young adults, often due to genetic factors.

An estimated 15% of Alzheimer’s patients carry two copies of APOE4, meaning those cases “can be tracked back to a cause and the cause is in the genes,” Fortea said.