Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39.

A recent research finding adds to evidence that brain inflammation is a major driver of neurodegenerative disorders such as ...

R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling ...

A study reveals that the APOE3-R136S mutation delays Alzheimer’s disease by inhibiting the cGAS-STING immune pathway. This ...

A rare gene mutation that delays Alzheimer's disease does so by damping inflammatory signaling in brain-resident immune cells, according to a preclinical study led by investigators at Weill ...

A groundbreaking study has revealed that a rare gene variant, APOE3-R136S, delays the onset of Alzheimer's disease by ...

Three Siblings, One Fatal Gene: A Family’s Fight Against Early-Onset Alzheimer’s Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms ...

June is Alzheimer's and Brain Awareness Month. Colbie Schueneman, 6, is sharing her story with KIF1A, also known as KAND.

Dec. 1, 2021 — A gene mutation linked to Alzheimer's disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study.

In 2023, neurologists at a memory clinic in China diagnosed a 19-year-old with what they believed to be Alzheimer's disease – ...

That may be because most mouse models of Alzheimer’s disease harbor the Swedish mutation. This has so far hindered efforts to study the beneficial effects of the Icelandic mutation. Now, by ...