An Italian family hit hard by Alzheimer’s offers clues about a potential genetic cause of the neurodegenerative disease, a ...

A study from UC San Diego discovered that the PHGDH gene, previously linked to Alzheimer’s as a biomarker, actually plays a ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in ...

Nature Outlook: Alzheimer’s disease The early onset of the disease ... people — all blood relatives — shared a mutation in the gene presenilin 1 (PSEN1) 2. Mutations in presenilin genes ...

For many years, Arboleda-Velasquez and an international team of scientists have been studying a large cohort of related individuals in Colombia who have ADAD caused by a mutation called ... new ...

A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that ...

A micrograph showing inflammatory responses in the cortex of the new model mouse. Alzheimer's disease patients and mouse ...

The causes of Alzheimer’s disease ... gene expression. This discovery, published in the journal Cell00397-6), opens the door to an entirely new way to detect and possibly treat the disease ...

Using AI, researchers at San Diego University revealed that there is a hidden DNA-binding function unrelated to its known enzymatic activity.

Five of six DeMoe siblings have tested positive for early onset Alzheimer's disease, now the latest ... other siblings have the early onset genetic mutation,” McIntyre tells PEOPLE, noting ...

The vast majority of patients do not have a mutation in a known disease-causing gene; instead, they have “spontaneous” Alzheimer’s, and the causes for that are unclear. Discovering those ...