A novel treatment, an aldosterone synthase inhibitor, safely and consistently lowered blood pressure in individuals with ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

A new medication called lorundrostat has shown strong potential as a treatment for people with uncontrolled or resistant high ...

Lorundrostat is an oral aldosterone synthase inhibitor targeting the treatment of hypertension, obstructive sleep apnoea, and ...

What Is an Aldosterone Test? If you’re having any blood pressure problems, your doctor might order an aldosterone test. An aldosterone test measures the amount of the hormone aldosterone in your ...

The data from the Launch-HTN trial, announced at the 34th European Meeting on Hypertension and Cardiovascular Protection, ...

Lorundrostat, a novel therapy which blocks the production of aldosterone from the adrenal glands, demonstrated clinically meaningful and sustained reductions in blood pressure in 1,083 patients with ...

Aldosterone, a hormone produced by the triangular adrenal glands, might be the key target. In the observational study, researchers analyzed health data from 3,680 people with chronic kidney ...

Perspectives from Keith Churchwell, MD, FAHA Keith C. Ferdinand, MD CHICAGO — The investigational aldosterone synthase inhibitor lorundrostat effectively lowered 24-hour BP for adults with well ...

It is unclear whether these beneficial effects are due solely to aldosterone blockade, as MR has a similar affinity for cortisol. We examined the relationships between plasma and urinary steroid ...

More information: Roshan A. Ananda et al, Relationship Between Renin, Aldosterone, Aldosterone-to-Renin Ratio and Arterial Stiffness and Left Ventricular Mass Index in Young Adults, Circulation ...

Agarwal explains that low levels of a hormone called aldosterone might be behind your constant urge to eat salty food. In her words, “Your cravings are your body’s way of whispering what it needs.