A phase 2 trial evaluated the efficacy and safety of lorundrostat in hypertensive patients with chronic kidney disease (CKD) and albuminuria.

Aldosterone, a hormone made by the adrenal glands, has been linked to kidney disease in people with diabetes, and now in those without it. Skip to Main Content. Mental Health. FDA.

Even in people without high blood pressure, subclinical primary aldosteronism is linked to a significantly higher risk for ...

Aldosterone helps balance blood levels of sodium and potassium, researchers said. Levels that are too high can cause people ...

Hyperaldosteronism is when your adrenal glands make too much aldosterone hormone. Learn about the causes, symptoms, and treatment options for this condition today.

Aldosterone, a steroid hormone produced by the zona glomerulosa layer of the adrenal cortex, plays an important role in maintaining sodium and water homeostasis.

A recent review by Shibata and Itoh 8 provides details of the current theoretical framework surrounding mineralocorticoid activity in hypertension. We limit our review to mechanisms that would be ...

Aldosterone has been shown to be involved in the process of LVH; in the canine model of CHF, eplerenone has been shown to cause reversal of LVH and remodeling of the left ventricle.

Aldosterone secretion rates were measured one day before and on each of the two infusion days in most subjects, except in 1 (M.F.), in whom aldosterone determinations were omitted.

“We know aldosterone plays an outsize role in CVD and in hypertension in general,” Luke J. Laffin, MD, co-director of the Center for Blood Pressure Disorders at Cleveland Clinic, told Healio.

Aldosterone is a hormone that the body normally produces. It's present in all of us. It's important because it helps us hold on to salt and water. Patients with heart failure, particularly those ...

AMPHENONE was synthesized in 1950 by Allen and Corwin1 and has been shown to possess a high degree of biologic activity in animals2 3 4 and man.5 6 7 In animals the compound has been shown to affec ...