Angiotensin converting enzyme inhibitors and angiotensin receptor blockers are commonly used to treat hypertension and/or a range of progressive end-organ diseases. The success of each of these ...

5) and to study its enzymatic properties, and soon thereafter, Miguel Ondetti and I began a fruitful collaborative effort to discover or design potent and specific inhibitors of ACE. The modern ...

There remains an art as much as a science to the use of these drugs. The science behind ACE inhibitor use is well accepted, the art, however, is a work in progress, with many subtleties to use ...