When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the hemoglobin protein causes the red blood cells to lose oxygen and warp into a sickle shape during periods of ...
The abnormally shaped ... of the sickle-cell trait. Annals of Internal Medicine 7, 769–778 (1933) Herrick, J. Peculiar elongated and sickle-shaped red blood corpuscles in a case of severe ...
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