Patients exhibit low serum ALP activity and present with symptoms such as rickets in children and osteomalacia in adults. Wilson's disease: An inherited disorder of copper metabolism where copper ...

HPP is a genetic disease caused by deficient ALP activity, resulting from pathogenic mutations in the ALPL gene, which leads to multi-systemic clinical complications including deficient bone ...

Subnormal ALP levels are associated with ... Low levels can indicate: Lead Poisoning: Lead exposure inhibits 5'-NT activity. Lead interferes with several enzymatic processes, including those ...