Sam Darnold throws for 242 yards and a touchdown, and Seattle withstands a late rally by Kyler Murray and Arizona to win, 23-20, on Myers’ kick as time expires.

The Seahawks blew a 14-point fourth-quarter lead but still won their eighth straight over their NFC West rivals.

Thursday Night Football schedule, TV channel, time, streaming information for Seattle Seahawks vs Arizona Cardinals NFL Week 4 game on Sept. 25, 2025.

It came down to a field goal as Sam Darnold and the Seattle Seahawks went into the desert and came away with a hard-fought Thursday night win, defeating the Arizona Cardinals 23–20 at State Farm Stadium to improve to 3–1 on the season.

"Meanwhile, the Seattle Seahawks outscored the Pittsburgh Steelers and Saints 75-30 over the last two weeks. Running back Zach Charbonnet, cornerback Devon Witherspoon and safety Julian Love could return for the Seahawks in this matchup. Take Seattle for the win."

The SportsLine projection model has revealed its Arizona vs. Seattle picks for the 2025 NFL Week 4 'Thursday Night Football' game

Arizona Cardinals wide receiver Marvin Harrison Jr. contributed to two early turnovers in Thursday night's Week 4 game against the visiting Seattle Seahawks.

The primetime lights were too bright for Jonathan Gannon's squad in their 23-20 loss in Week 4. The Cardinals are now 2-2 on the season with both losses coming within the NFC West.