The Arizona Wildcats and Iowa State Cyclones meet in a Week 5 Big 12 clash Saturday at Jack Trice Stadium in Ames, Iowa.

The Iowa State Cyclones passing game against the Arizona Wildcats pass defense will be a key to keep an eye on.

Preview the Sept. 27 matchup between the Iowa State Cyclones and Arizona Wildcats with predictions, odds, over/under, spread, betting lines and more.

A battle between a pair of undefeated teams is coming to Jack Trice Stadium this weekend. Arizona will visit No. 12 Iowa State for a Big 12 matchup on Saturday ...

This article was originally published on www.si.com/college/arizona as The History of Arizona-Iowa State on the Gridiron.

Arizona Wildcats are back from the bye week and will be facing the 4-0, No. 14-ranked Iowa State Cyclones for the first time since 1968 to open up their ...

Arizona is off to its best start since 2015, winning its three nonconference games by a combined 93 points. But now come the ...

Two of the top Big 12 scoring defenses are featured on Saturday, and our expert college football predictions expect a ...

The Arizona Wildcats and Iowa State Cyclones meet for the first time since 1968, now Big 12 opponents and both coming off ...

The No. 14 Iowa State Cyclones and the Arizona Wildcats square off in a matchup of Big 12 foes. How to watch Arizona (3-0) vs ...

Iowa State football confirmed which uniform color combination the team will wear in its Week 5 game vs. Arizona. See the look ...

What channel is Arizona vs Iowa State game on? Time, how to watch on TV, how to stream college football Week 5 Big 12 game Saturday, Sept. 27, 2025.