Red Hook is a suburban port census-designated place located on the east side of Saint Thomas in the East End subdistrict. It is the least populated town or CDP in the Virgin Islands with a population of 225 according to the 2020 Census. This east end CDP features an unofficial "town" of red-tiled roof homes and businesses dotting a rolling coastline that overlooks …Red Hook is a suburban port census-designated place located on the east side of Saint Thomas in the East End subdistrict. It is the least populated town or CDP in the Virgin Islands with a population of 225 according to the 2020 Census. This east end CDP features an unofficial "town" of red-tiled roof homes and businesses dotting a rolling coastline that overlooks Pillsbury Sound and the island of St. John. Red Hook hosts several hotels, marinas, a busy port, and other key items of the east side of St. Thomas.